Established in 2009,  the SAMRC/WITS Centre for Health Economics and Decision Science-PRICELESS SA(Priority Cost Effective Lessons for System Strengthening South Africa)  is an extramural research unit of the South African Medical Research Council, based at the School of Public Health at the University of the Witwatersrand in Johannesburg, South Africa. Our aim is to support the development of evidence-based information together with tools and methods for making decisions on how to use scarce resources to improve health for South Africa. Our multidisciplinary team includes health economists, clinicians, and researchers with backgrounds in sociology, anthropology, epidemiology, public health, health services and law. We have a strong academic record, and we engage with policymakers, the public and the media in our endeavour to strengthen insight and expertise for setting priorities for Southern Africa.